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3D Human Blood Brain Barrier.

$USD4,053 $USD3,525

The blood brain barrier (BBB) specifically regulates molecular and cellular flux between the blood and the nervous tissue. We develop and characterize a highly reproducible Human in vitro model of the BBB using co-cultures of primary Human brain endothelial cells (HBEC), Human brain pericytes, and Human brain astrocytes to study receptors involved in transcytosis across the endothelial cell monolayer. Many drugs developed to treat Central Nervous System (CNS) disorders are unable to reach the brain parenchyma in therapeutically relevant concentrations. The BBB protects brain nervous tissue from the fluctuation of plasma composition, from pathogenic agents, and maintains homeostasis of the brain parenchyma by restricting non-specific flux of ions, peptides, proteins and even cells into and out the brain.

Model Components:

* Culture Medium
* Frozen Model
* Suture Removal Kits

FOR RESEARCH USE ONLY
REGENERATION BIOLOGY PHARMACEUTICAL, RESEARCH LABS, PRODUCTS & SERVICES, ARE FOR IN VITRO AND CERTAIN NON-HUMAN IN VIVO XPERIMENTAL USE ONLY AND NOT INTENDED FOR USE IN ANY HUMAN CLINICAL INVESTIGATION, IAGNOSIS, PROGNOSIS, ORTREATMENT. THE ABOVE ANALYSES ARE MERELY TYPICAL GUIDES. THEY ARE NOT TO BE CONSTRUED AS BEING SPECIFICATIONS. ALL OF THE ABOVE INFORMATION IS, TO THE BEST OF OUR KNOWLEDGE, TRUEAND ACCURATE. HOWEVER, SINCE THE CONDITIONS OF USE ARE BEYOND OUR CONTROL, ALL RECOMMENDATIONS OR SUGGESTIONS ARE MADE WITHOUT GUARANTEE, EXPRESS OR IMPLIED, ON OUR PART. WEDISCLAIM ALL LIABILITY IN CONNECTION WITH THE USE OF THE INFORMATION CONTAINED HEREIN OR OTHERWISE, NDALL SUCH RISKS ARE ASSUMED BY THE USER. WE FURTHER EXPRESSLY DISCLAIM ALL ARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE. V1-09809. www.regenerationbiology.com

Regeneration Biology” Pharmaceutical, Research Labs, Products & Services, Manufacturing Antibodies. • 23418 Prairie Mall • Grande Prairie, AB T8V7G7 phone 888-866-4972 • e-mail sales@regenerationbiology.com

 

SKU: 826763007106 Category:

Description

3D BBB-Model” specifically regulates molecular and cellular flux between the blood and the nervous tissue. With a “three-dimensional” model of the “human blood-brain barrier” to analyse the transport of “nanoparticles” and “astrocyte” endothelial” interactions.

Product Details,
3D Human Blood Brain Barrier

CATALOG NUMBER: 3DB33002
APPLICATIONS: In vivo Like Assays
TYPE: 3D Cell/Tissue Models
STORAGE: Keep frozen in liquid nitrogen until plating
SHIPPING: Frozen (Dry Ice/Liquid Nitrogen)
SPECIES REACTIVITY: Human

Catalog #: 3DB33002
Storage: -80°C
Format: 6, 12 or 24 well.

Storing of BBB model thawing-sol and incubation medium.

BBB is stored at -80  and can be used within one month. Media is stored at below -20.

Product Sizes     List Price                A Special Price             Catalog #
6 well                    $2,035.5                   $1,770.00                 RGBBB-RB006
12 well                 $2,875.00                 $2,500.00                RGBBB-RB0012
24 well                 $4053.75                  $3,525.00                RGBBB-RB0024