Product Name Anti-Catenin Gamma (Plakoglobin) Antibody (Monoclonal, 15F11)
Mouse IgG monoclonal antibody for Catenin gamma (Plakoglobin), junction plakoglobin ( JUP) detection. Tested with WB, IHC-F, ICC in Human, bovine. No cross reactivity with other proteins.
Target Species Bovine, Human
Application IHC-F, ICC, WB
Recommended Detection Systems
We recommend Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(F).
*Blocking peptide can be purchased. Contact us for moreinformation
Immunogen Recombinant chicken plakoglobin.
Specificity No cross reactivity with other proteins
Pack Size 100?g/vial
Junction Plakoglobin(JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherincatenin complex, which is predominantly localized where actinfilaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes onchromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin