Product Name : Anti-COL4 Rabbit Polyclonal Antibody
Collagen IV is a major constituent of the basement membranes along with laminins and enactins. It is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio . It can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
ELISA: 1/200. IF: 1/80. Use on frozen mouse tissues (skin, liver). IHC-P: 1/500. RIA: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
|Antigen name||Collagen 4|
|Antigen synonyms||collagen of basement membrane,alpha-1 polypeptide,collagen alpha-1(IV) chain,COL4A1 NC1 domain,collagen IV,alpha-1 chain|
|Immunogen||Full length native protein (extracted and purified from tumor tissues) (Mouse).|
|Storage temperature||Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.|
|Tested applications||Radio Immunoassay|