Anti-COL4A1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

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Description

Product Name : Anti-COL4A1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ‘chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
Recommended Dilutions: IF(IHC-P): 1:50-200
Antigen symbolCOL4A1
Antigen nameCollagen, type IV, alpha 1
Antigen synonymsBSVD,RATOR
Antibody typePrimary
ClonalityPolyclonal
ConjugationFITC (Fluorescein Isothiocyanate)
ReactivityHuman,Rat,Mouse
HostRabbit
Gene ID1282
IsotypeIgG
ImmunoChemistryYes
Immunogen1620-1665/1669
Formliquid
PurificationPurified by Protein A
Concentration1 ?g/?l
Cross adsorptionNo
Storage bufferAqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperatureStore at 4°C for 12 months
Shipping temperature4°C