Anti-COL6A1 Rabbit Polyclonal Antibody

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SKU: coll-0086 Category:

Description

Product Name : Anti-COL6A1 Rabbit Polyclonal Antibody

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1000
Antigen symbolCOL6A1
Antigen nameCollagen type VI alpha 1
Antigen synonymsCollagen alpha-1(VI) chain,COL6A1
Antibody typePrimary
ClonalityPolyclonal
ConjugationUnconjugated
ReactivityHuman
HostRabbit
IsotypeIgG
Western blotYes
ELISAYes
ImmunoChemistryYes
ImmunoPrecipitationYes
ImmunoFluorescenceYes
Gel shiftYes
Flow cytometryYes
ChIPYes
NeutralisationYes
ImmunogenKLH conjugated synthetic peptide between 831-858 amino acids from the C-terminal region of human COL6A1
FormLiquid
Molecular weight108.53 kDa
PurificationAmmonium sulfate precipitation, Size-exclusion – Dialysis
ConcentrationLot-specific
Cross adsorptionNo
Storage bufferPBS with 0.09% Sodium azide
Storage temperatureMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at –20 °C
Tested applicationsImmunohistochemistry