Anti-COL7A1 Goat Polyclonal Antibody

$USD2,763

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SKU: coll-0035 Category:

Description

Product Name : Anti-COL7A1 Goat Polyclonal Antibody

This antibody is predicted to react with canine, human, mouse and porcine based on sequence homology. This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

 

Western Blot: 0.1-1.5 ug/ml
Antigen symbolCOL7
Antigen nameCollagen, type VII
Antigen synonymsdominant and recessive),alpha 1 (epidermolysis bullosa,type VII,collagen,EBD1,alpha 1,collagen VII,EBDCT,Collagen,COL7A1,long chain collagen,alpha-1 polypeptide,LC collagen,alpha 1 type VII collagen,EBR1,dystrophic,HGNC:2214
Antibody typePrimary
ClonalityPolyclonal
ConjugationUnconjugated
ReactivityRat
HostGoat
IsotypeIgG
Western blotYes
Cross adsorptionNo
Storage bufferTBS, pH 7.3, with 0.5% BSA and 0.02% Sodium azide
Storage temperature–20 °C, avoid freeze/thaw cycles