Anti-CTSK Rabbit Polyclonal Antibody

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Description

Product Name : Anti-CTSK Rabbit Polyclonal Antibody

Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996). Cathepsin K is synthesized as an inactive proenzyme (35.1 kDa) that is converted to its mature active form (23.6 kDa) by proteolytic cleavage of its 99-amino-acid propeptide domain. The in-vitro processing of procathepsin K to mature cathepsin K is autocatalytic.
Antigen symbolCTSK
Antigen nameCathepsin K
Antibody typePrimary
ClonalityPolyclonal
ConjugationUnconjugated
ReactivityHuman
HostRabbit
Gene ID1513
IsotypeIgG
Western blotYes
ImmunogenRecombinant protein Procathepsin (19-329aa) (BV-M64)
FormLiquid
PurificationAffinity Purified Antibody
Concentration0.5 mg/ml
Storage temperature-20 °C
Shipping temperaturegel pack