Anti-PECAM1 Mouse Monoclonal Antibody

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SKU: hec-060 Category:

Description

Product Name : Anti-PECAM1 Mouse Monoclonal Antibody

CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets.CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).
Western Blot:1:500 – 1:2,000 <br>IHC(P):1:500 – 1:2,000<br>ELISA:Propose dilution 1:10,000.<br>Determining optimal working dilutions by titration test.
Ascitic fluid containing 0.03% sodium azide.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Antigen symbolPECAM1
Antigen nameplatelet/endothelial cell adhesion molecule 1
Antigen synonymsPECAM1
Antibody typePrimary
ClonalityMonoclonal
ConjugationUnconjugated
Clone2F7B2
ReactivityHuman
HostMouse
Gene IDP16284
IsotypeIgG1
Western blotYes
ELISAYes
ImmunoChemistryYes
ImmunogenNi-NTA purified recombinant CD31 expressed in E. Coli strain BL21 (DE3).
Storage bufferAscitic fluid containing 0.03% sodium azide.
Storage temperatureCD31 monoclonal antibody can be stored at –20 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Shipping temperature4 °C