Anti-TEK Rabbit Polyclonal Antibody


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SKU: hec-056 Category:


Product Name : Anti-TEK Rabbit Polyclonal Antibody

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Western Blot: 1:500~1:1000
Antigen symbolTEK
Antigen nameTEK tyrosine kinase, endothelial
Antigen synonymsTEK
Antibody typePrimary
Gene IDQ02763
Western blotYes
ModificationTyr 992
ImmunogenTIE2 (phospho Tyr992) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 992 (E-V-Y (p)-V-K) derived from Human TIE2.
Molecular weight126 kDa
PurificationAntibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration1 mg/mL
Storage bufferAntibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage temperatureStore antibody at –20 °C for up to one year.
Shipping temperature4 °C