Product Name : Anti-VEGF Human Monoclonal Antibody
Bevacizumab (Avastin) is a recombinant humanized monoclonal IgG1 antibody. Bevacizumab, targets the cell surface protein called vascular endothelial growth factor (VEGF) results in suppression of tumor growth. VEGF plays an essential role in developmental angiogenesis and is also important for reproductive and bone angiogenesis. Avastin is used to treat various cancers like metastatic colorectal cancer, non-squamous non–small cell lung cancer, metastatic breast cancer, glioblastoma and metastatic renal cell carcinoma.
|Antigen name||Vascular endothelial growth factor A splice variant VEGF 117|
|Immunogen||Recombinant human VEGF|
|Purification||human IgG1 was expressed in a human cell line. IgG was purified from CHO cell culture supernatant by protein A chromatography.|
|Storage temperature||–20 °C|
|Shipping temperature||gel pack|