Human Recombinant CTHRC1 (from Cells)

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Description

Product Name : Human Recombinant CTHRC1 (from Cells)

Collagen triple helix repeat-containing protein 1 is a protein that in humans is encoded by the CTHRC1 gene. It acts as a negative regulator of collagen matrix deposition. It may cause the disease of Barrett esophagus . Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes.
  • Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.
Protein/peptide nameCTHRC1
Protein synonymsProtein NMTC1,Collagen triple helix repeat-containing protein 1,NMTC1,CTHRC1
Protein/peptide typeRecombinant
SpeciesHuman
SourceCells
SequenceSer31-Lys243
Endotoxin content<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Purity> 95% as determined by reducing SDS-PAGE
FormulationLyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Molecular weight24.1 kD
Storage conditionsLyophilized protein should be stored at ?20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at ?20 °C for 3 months.
Tag sequenceC-6 His tag
Tested applicationsused for biological assays
Molecular weight24.1 kD