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Human Recombinant VEGF 121

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$920.31

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Product Name : Human Recombinant VEGF 121

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF 121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. Recombinant Human VEGF 121 is a 28.4 kDa, disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains.

Protein/peptide name VEGF 121
Protein synonyms Folliculostellate cell-derived growth factor,Vascular Endothelial Growth Factor,VEGF-A,Glioma-derived endothelial cell mitogen
Protein/peptide type Recombinant
Species Human
Source E. coli
Conjugation Unconjugated
Gene ID 7422
Sequence APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENCDKPR R
Animal-free Y
Endotoxin level low
Biological activity Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4 ng/ml.
Purity 98%
Formulation Lyophilized
Molecular weight 28.4 kDa
Shipping temperature Ambient
Molecular weight 28.4 kDa
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