Human Recombinant VEGF 165

$USD920

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SKU: hec-006 Category:

Description

Product Name : Human Recombinant VEGF 165

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Human VEGF 165 is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

Protein/peptide nameVEGF 165
Protein synonymsFolliculostellate cell-derived growth factor,Vascular Endothelial Growth Factor,VEGF-A,Glioma-derived endothelial cell mitogen
Protein/peptide typeRecombinant
SpeciesHuman
SourceE. coli
ConjugationUnconjugated
Gene ID7422
SequenceAPMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Animal-freeY
Endotoxin levellow
Biological activityDetermined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml.
Purity98%
FormulationLyophilized
Molecular weight38.2 kDa
Shipping temperatureAmbient
Molecular weight38.2 kDa