Product Name : Human Recombinant VEGFD
Vascular endothelial growth factor D (VEGF-D) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. It is highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas. VEGF-D is growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. It undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3 receptors.
- Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.
Protein/peptide nameVEGFDProtein synonymsFIGF,Vascular Endothelial Growth Factor D,c-Fos-Induced Growth Factor,VEGFD,VEGF-DProtein/peptide typeRecombinantSpeciesHumanSourceCellsSequencePhe93-Ser201Endotoxin content<0.1 ng/ug (1 IEU/ug) as determined by LAL test.Purity> 95% as determined by reducing SDS-PAGEFormulationLyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Molecular weight12.18 kDStorage conditionsLyophilized protein should be stored at ?20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at ?20 °C for 3 months.Tag sequenceC-6 His tagTested applicationsBioassay